Development of a Packed Bed Reactor for the Synthesis of Peptides and Foldamers: A Revolutionary Reduction of the Amino Acid ExcessWednesday, 18 February 2015 at 16:00 Add to Calendar ▼2015-02-18 16:00:002015-02-18 17:00:00Europe/LondonDevelopment of a Packed Bed Reactor for the Synthesis of Peptides and Foldamers: A Revolutionary Reduction of the Amino Acid ExcessDiscovery Chemistry Congress in Berlin, GermanyBerlin, GermanySELECTBIOenquiries@selectbiosciences.com A highly efficient continuous-flow technique for the synthesis of peptides was developed which allows the application of only 1.5 equivalents of amino acids during coupling, while yielding virtually quantitative conversions. Difficult sequences and ß-peptide foldamers with alicyclic side-chains were synthesized in excellent yields. |