Paper-based Devices for Isolation and Characterization of Extracellular Vesicles and Clinical ApplicationsFriday, 8 April 2016 at 14:00 Add to Calendar ▼2016-04-08 14:00:002016-04-08 15:00:00Europe/LondonPaper-based Devices for Isolation and Characterization of Extracellular Vesicles and Clinical ApplicationsExosomes and Liquid Biopsies Asia 2016 in Taipei, TaiwanTaipei, TaiwanSELECTBIOenquiries@selectbiosciences.com We have developed a paper-based immunoaffinity platform for separating subgroups of EVs that is easy, efficient, and requires sample volumes as low as 10 µL. Biological samples can be pipetted directly onto paper test zones that have been chemically modified with capture molecules that have high affinity to specific EV surface markers. We have validated the assay by using different approaches such as scanning electron microscopy (SEM), paper-based enzyme-linked immunosorbent assays (P-ELISA), and transcriptome analysis. These paper-based devices would enable the study of EVs in the clinic, what we will mention in the talk as well, and the research setting to help advance our understanding of EV functions in health and disease. |