NanoVelcro-Embedded Microchips for Detection and Characterization of Circulating Tumor CellsThursday, 7 April 2016 at 13:30 Add to Calendar ▼2016-04-07 13:30:002016-04-07 14:30:00Europe/LondonNanoVelcro-Embedded Microchips for Detection and Characterization of Circulating Tumor CellsExosomes and Liquid Biopsies Asia 2016 in Taipei, TaiwanTaipei, TaiwanSELECTBIOenquiries@selectbiosciences.com Inspired by the nanoscale interactions observed in the tissue microenvironment, our research team at UCLA pioneered a unique concept of “NanoVelcro” cell-affinity substrates, in which CTC capture agent-coated nanostructured substrates were utilized to immobilize CTCs with high efficiency. The working mechanism of NanoVelcro cell-affinity substrates mimics that of VelcroTM – when the two fabric strips of a Velcro fastener are pressed together, tangling between the hairy surfaces on two strips leads to strong binding. Through continuous evolution, 3 generations of NanoVelcro CTC Chips have been established to achieve different clinical utilities. My presentation will summarize the continuous evolution of NanoVelcro CTC Assays from the emerge of the original idea all the way to their applications in cancer research and diagnosis. We envision that NanoVelcro CTC Assays will lead the way for powerful and cost-efficient diagnostic platforms for researchers to better understand underlying disease mechanisms and for physicians to monitor real-time disease progression. |