| Conferences \ EV-based Diagnostics, Delivery & Therapeutics \ Agenda \ Susanne Gabrielsson |
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Optimizing Dendritic Cell-Derived Exosomes For Cancer ImmunotherapyMonday, 17 February 2020 at 12:15 Add to Calendar ▼2020-02-17 12:15:002020-02-17 13:15:00Europe/LondonOptimizing Dendritic Cell-Derived Exosomes For Cancer ImmunotherapyEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.comPeptide loaded exosomes are promising cancer treatment vehicles, however, low T cell responses in human clinical trials indicate a need to further understand exosome-induced immunity. We previously demonstrated that antigen-loaded exosomes carry whole protein antigens and require B cells for induction of antigen-specific T cells. I will discuss our latest data where we investigated the need for different immune related molecules on exosomes to induce T cell responses and tumor rejection in the B16 mouse melanoma model. Our data demonstrate ways to increase the feasibility of exosome-based therapeutic approaches in cancer. |
Add to Calendar ▼2020-02-17 00:00:002020-02-18 00:00:00Europe/LondonEV-based Diagnostics, Delivery and TherapeuticsEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com