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SELECTBIO Conferences Extracellular Vesicles & Nanoparticle Therapeutics Europe 2022

Samir EL-Andaloussi's Biography



Samir EL-Andaloussi, Associate Professor, Karolinska Institutet

Samir EL Andaloussi received his PhD in 2008 in Neurochemistry with Molecular Neurobiology at Stockholm University. After a postdoctoral stint at Karolinska Institutet, he moved to University of Oxford to work with extracellular vesicles (EVs). Since 2013 Associate Professor Samir is a Principal Investigator for a growing lab at Karolinska Institutet, now with nearly 20 employees. His lab primarily focuses on developing non-viral drug delivery systems for nucleic acids and proteins with particular focus on production of engineered exosomes for delivery of biotherapeutics. In addition, Samir in one of the Founders of Evox Therapeutics, a company developing engineered EVs for treatment of genetic diseases.

Samir EL-Andaloussi Image

Bioengineering of Extracellular Vesicles

Tuesday, 25 October 2022 at 12:15

Add to Calendar ▼2022-10-25 12:15:002022-10-25 13:15:00Europe/LondonBioengineering of Extracellular VesiclesExtracellular Vesicles and Nanoparticle Therapeutics Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

Extracellular vesicles (EVs) have emerged as important mediators of intercellular communication due to their ability to transfer bioactive lipids, proteins and different species of RNA into cells. As such, EVs can be harnessed for the delivery of macromolecular drugs. Adapting EVs for drug delivery requires cellular engineering that allows for selective loading of biotherapeutics inside or on the surface of EVs. This presentation will cover our recent developments in EV engineering, with focus on selective protein loading, as well as strategies for their purification and characterization. In addition to addressing PK, PD and functional delivery of EVs in normal and diseased mice, strategies to enhance tissue targeting and extending plasma half-life of circulating EVs will be discussed.


Add to Calendar ▼2022-10-24 00:00:002022-10-25 00:00:00Europe/LondonExtracellular Vesicles and Nanoparticle Therapeutics Europe 2022Extracellular Vesicles and Nanoparticle Therapeutics Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com