Alain Brisson,
Professor Emeritus,
University of Bordeaux
Alain Brisson has held academic positions in Grenoble, Strasbourg, Groningen and Bordeaux. His research has focused on the elucidation of biological processes occurring at cell membranes by combining molecular imaging and quantification methods. His current research focuses on extracellular vesicles and exosomes, with the objective to improve our understanding on this new class of sub-cellular entities. His group has pioneered original methods of immuno-cryo-electron microscopy and flow cytometry allowing to image and quantify EV in complex media. His main objectives are to deliver standardized methods of EV characterization, identify disease-specific EV signatures and exploit the potential of EV in drug delivery.
Contribution of Immuno-Cryo-Electron Microscopy to the EV Field
Monday, 13 November 2023 at 09:30
Add to Calendar ▼2023-11-13 09:30:002023-11-13 10:30:00Europe/LondonContribution of Immuno-Cryo-Electron Microscopy to the EV FieldExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Extracellular vesicle (EV) samples isolated from body fluids or conditioned media are heterogeneous in cell origin, membrane compartment origin, size, molecular composition and functional properties. Given the diversity of biological functions and biomedical applications borne by EV, there is an urgent need for efficient and reliable methods of EV characterization and isolation, to improve our understanding on EV and fully exploit their potential. Our group has pioneered the use of cryo-transmission electron microscopy (cryo-EM), immuno-gold labeling and flow cytometry for imaging and quantifying EV. In this presentation, I will first summarize the main contribution of immuno-cryo-EM to the EV field, helping to answer the question “What do contain EV samples?”. Next, I will present recent results and discuss our attempts to identify EV-based biomarkers in sickle cell disease and preeclampsia.
Add to Calendar ▼2023-11-13 00:00:002023-11-14 00:00:00Europe/LondonExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023Extracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2023-11-13 09:30:002023-11-13 10:30:00Europe/LondonContribution of Immuno-Cryo-Electron Microscopy to the EV FieldExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
