Jean-Thomas Issenhuth's Biography

Jean-Thomas Issenhuth, Key Account Manager EMEA, Polyplus-Transfection

Jean-Thomas obtained a master’s degree in Biochemistry and a Ph.D in Chemistry from the University of Strasbourg (2008). He complemented his studies with several post-docs working on different projects in chemistry with a focus on organometallic chemistry, enantioselective-catalysed reactions, and polymerization. Since 2013 he joined several international sales departments acting first as Business Manager and recently also as Key Account Manager where he has the chance to manage and grow a portfolio of major accounts in the EMEA zone within Polyplus-transfection.

Cationic Lipids Offer New Possibilities in Liposome and LNP Engineering for RNA Therapeutics

Tuesday, 14 November 2023 at 12:00

Add to Calendar ▼2023-11-14 12:00:002023-11-14 13:00:00Europe/LondonCationic Lipids Offer New Possibilities in Liposome and LNP Engineering for RNA TherapeuticsExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

Lipid-based nanoparticles (LNPs) represent one of the most promising RNA delivery systems, not only due to their efficacy, but also to the ease of production achieved through precise controlled mixing technique known as microfluidics and the scalability of production. Still, they present some limitations related to toxicity, targeting, limited biodistribution through systemic administration which mainly results in liver uptake. Polyplus^® has recently developed a library of cationic lipids (LipidBrick^®), which represents a remarkable innovation compared with conventional cationic lipids by ensuring reduced toxicity of LNPs and extending their use beyond the liver.

Add to Calendar ▼2023-11-13 00:00:002023-11-14 00:00:00Europe/LondonExtracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023Extracellular Vesicles and Nanoparticle-based Therapeutics Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

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