Functional Replacement of 5-azaC-dR by 2´-deoxyriboguanylurea in the Inhibition of Human Dnmt1, Epimutagenesis, Mutagenesis, and Fragile Site InductionThursday, 19 April 2012 at 11:45 Add to Calendar ▼2012-04-19 11:45:002012-04-19 12:45:00Europe/LondonFunctional Replacement of 5-azaC-dR by 2´-deoxyriboguanylurea in the Inhibition of Human Dnmt1, Epimutagenesis, Mutagenesis, and Fragile Site InductionSELECTBIOenquiries@selectbiosciences.com 5-aza-2´-deoxycytidine is an inhibitor of DNA methylation, a mutagen, an epimutagen, a carcinogen, an inducer of fragile sites and a chemotherapeutic agent. Each of these functions can be replaced in human cells by 2´-deoxyriboguanylurea: its the primary breakdown product. |