Targeting Leukemia Oncogene Expression with Bromodomain InhibitorsThursday, 9 May 2013 at 14:45 Add to Calendar ▼2013-05-09 14:45:002013-05-09 15:45:00Europe/LondonTargeting Leukemia Oncogene Expression with Bromodomain InhibitorsSELECTBIOenquiries@selectbiosciences.com Bromodomain inhibitors disrupt the association of chromatin-binding proteins with transcriptionally active regions of the genome. We have developed JQ1, an inhibitor of BET bromodomains; JQ1 induces a dramatic and selective decrease in oncogene expression in leukemia cells. |