Jean Lewis,
Associate Director, Research,
Biological Dynamics
Dr. Lewis is an Associate Director of Research at Biological Dynamics, Inc., where her team is developing exosome-based liquid biopsy assays using a proprietary platform. Her work has shown the potential utility of EV-protein biomarkers in non-invasive diagnosis of Alzheimer’s disease, infection, and cancer. Recently, her research has been directed towards identifying EV biomarkers for early-stage cancer liquid biopsy. Dr. Lewis obtained her Ph.D. in Biochemistry from the University of Pennsylvania. She started as an NIH National Research Service Award postdoctoral fellow at the Scripps Research Institute, where she conducted research in cancer cell metastasis and was later awarded both an NCI Independent Research Award and a Pardee Cancer Foundation grant. In a subsequent appointment at the UC San Diego Nanoengineering Department, she focused on developing EV-based immunoassays for cancer diagnostics.
Multi-Cancer Early Detection Based on a Classifier for Extracellular Vesicle Biomarkers
Wednesday, 2 March 2022 at 11:00
Add to Calendar ▼2022-03-02 11:00:002022-03-02 12:00:00Europe/LondonMulti-Cancer Early Detection Based on a Classifier for Extracellular Vesicle BiomarkersCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Simultaneous detection of multiple, early-stage cancers was tested using extracellular vesicle (EV) bound protein markers from plasma purified by an alternating current electrokinetic (ACE) microarray. In a case-control study, this method detected 95.7% of pancreatic, 75.0% of ovarian, and 43.8% of bladder cancers at 99.5% specificity, all at stage I. The initial results suggest that this liquid biopsy screen may have great promise for early stage, multi-cancer screening.
Add to Calendar ▼2022-03-01 00:00:002022-03-02 00:00:00Europe/LondonCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022Circulating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2022-03-02 11:00:002022-03-02 12:00:00Europe/LondonMulti-Cancer Early Detection Based on a Classifier for Extracellular Vesicle BiomarkersCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
