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SELECTBIO Conferences Fragment Based Lead Discovery

Andreas Heine's Biography



Andreas Heine, Head of X-ray Crystallography, Philipps Universitat Marburg

Since 2002 Head of X-ray crystallography in the laboratory of Prof. G. Klebe, Institute of Pharmaceutical Chemistry, Philipps-University Marburg 1999-2002 Assistant Professor in the Department of Molecular Biology, The Scripps Research Institute, La Jolla. 1993-1999 Post-doc at the Scripps Research Institute, La Jolla in the laboratory of Prof. I.A. Wilson. 1993 Richard-Zsigmondy Award” for doctoral dissertation 1990-1993 Doctoral thesis: Synthesis and structure investigation of metastable reaction intermediates. Advisor Prof. G.M. Sheldrick, Dept. of Inorganic Chemistry, Göttingen University. Master thesis: Crystallization and X-ray structure investigation of boron and nitrogen compounds. Advisor Prof. G.M. Sheldrick, Dept. of Inorganic Chemistry, Göttingen University 1986-1987 University of California at Berkeley recipient of an “Education Abroad Program” fellowship; Reciprocal student at the University of California Berkeley 1983-1990 Chemistry student, Georg-August University Göttingen.

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Molecular Probes as Starting Point for Structure-Based Lead Development

Wednesday, 14 March 2012 at 10:00

Add to Calendar ▼2012-03-14 10:00:002012-03-14 11:00:00Europe/LondonMolecular Probes as Starting Point for Structure-Based Lead Development SELECTBIOenquiries@selectbiosciences.com

Highly soluble probe molecules were selected to experimentally map out protein binding pockets to detect hot spots of binding. Protein kinase A in complex with phenol as molecular probe served as a starting point for further structure-based lead development.


Add to Calendar ▼2012-03-13 00:00:002012-03-14 00:00:00Europe/LondonFragment Based Lead DiscoverySELECTBIOenquiries@selectbiosciences.com