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Development and Scale-up of a Continuous Process: From Concept to Implementation

Friday, 29 April 2011 at 11:15

Add to Calendar ▼2011-04-29 11:15:002011-04-29 12:15:00Europe/LondonDevelopment and Scale-up of a Continuous Process: From Concept to ImplementationFlow Chemistry Congress in Boston Boston SELECTBIOenquiries@selectbiosciences.com

The development of a synthetic route to tasisulam sodium (5-bromo-thiophene-2-sulfonic acid 2, 4-dichlorobenzoylamide sodium salt) utilizing continuous Schotten-Baumann reaction conditions is presented. Batch development, continuous proof of concept, 50 g/day lab scale demonstration and 5 kg/day commercial scale runs will be described.