Hannes P. L. Gemoets was born in Ghent (1991), Belgium. In 2013, he received a M. Sc. degree in Chemical Engineering (cum laude) at the KU Leuven (Faculty of Engineering Technology Ghent). Later that year, he moved to the Netherlands to pursue his Ph.D. at the Eindhoven University of Technology (TU/e) in the Micro Flow Chemistry & Process Technology group, under the supervision of Prof. Timothy Noël and Prof. Volker Hessel. His research focused on the development of novel continuous-flow methods for C–H functionalization strategies (i.e. C–H activation and photoredox catalysis). As a next step in his career, Hannes joined the Research & Development division of Creaflow located in Deinze, Belgium. As R&D Engineer, his work focuses on the design and development of innovative and scalable continuous-flow (photo)reactors.
The HANU-Reactor: Development of a Scalable Continuous-Flow Photoreactor
Thursday, 14 November 2019 at 10:30
Add to Calendar ▼2019-11-14 10:30:002019-11-14 11:30:00Europe/LondonThe HANU-Reactor: Development of a Scalable Continuous-Flow PhotoreactorFlow Chemistry Asia 2019 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com
In the last decade, continuous-flow photochemistry has received much attention from researchers in academia as well as industry. With the groundwork now in place, the focus has been shifted to the realization of scalable photochemistry, and in this context, the HANU-reactor was developed. This pulsating-flow plate reactor contains static mixing elements that induce a split-and-recombine flow path, and is equipped with a large window lid for maximum light exposure. The synergetic use of the reactor geometry with a pulsating flow regime, results in plug flow behavior combined with intense mixing, regardless of its net flow rate. The innovative design allows the user to operate the reactor at both short and very long light exposure times, without compromising the mixing efficiency or the need for flow recirculation. To demonstrate its potential, an intramolecular [2+2]-cycloaddition was performed, producing an impressive 2.3 kg of Cookson’s diketone per day, utilizing a single 15 mL lab-scale HANU-reactor. Thanks to the innovative design, the HANU-reactor can be linearly scaled. Preparative photochemistry is now readily accessible by simply widening its process channel without the need to change any process parameters.[4] In addition, the pulsatile flow expands the window to heterogeneous reaction processing (e.g. heterogeneous photocatalyst). Furthermore, the window lid allows visual inspection as well as application of non-invasive, through-window inline spectroscopic PAT.
Add to Calendar ▼2019-11-14 00:00:002019-11-15 00:00:00Europe/LondonFlow Chemistry Asia 2019Flow Chemistry Asia 2019 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2019-11-14 10:30:002019-11-14 11:30:00Europe/LondonThe HANU-Reactor: Development of a Scalable Continuous-Flow PhotoreactorFlow Chemistry Asia 2019 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com
