Profiling Genome-wide Target Specificities of CRISPR/Cas9 Nucleases in Human CellsWednesday, 7 October 2015 at 09:45 Add to Calendar ▼2015-10-07 09:45:002015-10-07 10:45:00Europe/LondonProfiling Genome-wide Target Specificities of CRISPR/Cas9 Nucleases in Human CellsGenome Engineering in Hanover, GermanyHanover, GermanySELECTBIOenquiries@selectbiosciences.com We show that CRISPR-Cas9 off-target effects can be avoided by modifying guide RNA and using purified Cas9 protein. We also present Digenome-seq to profile genome-wide Cas9 off-target effects in human cells. |