NMR as a Tool for Examining Mechanisms of Transport and Inhibition in CLC “Chloride Channels”Tuesday, 27 September 2011 at 14:15 Add to Calendar ▼2011-09-27 14:15:002011-09-27 15:15:00Europe/LondonNMR as a Tool for Examining Mechanisms of Transport and Inhibition in CLC “Chloride Channels”Ion Channel Targets in San FranciscoSan FranciscoSELECTBIOenquiries@selectbiosciences.com A detailed mechanistic understanding of ion transport via CLC “chloride channels” would facilitate development of therapeutics to treat CLC-mediated disorders. Towards this goal, I have developed NMR-based systems to assess how binding of various ligands influence CLC conformational change. |