Circulating Tumor DNA Methylation Markers for Diagnosis and Prognosis of Hepatocellular CarcinomaThursday, 28 March 2019 at 16:30 Add to Calendar ▼2019-03-28 16:30:002019-03-28 17:30:00Europe/LondonCirculating Tumor DNA Methylation Markers for Diagnosis and Prognosis of Hepatocellular CarcinomaLiquid Biopsies 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com We identified an HCC-specific methylation marker by comparing HCC tissue and normal blood leukocytes and showed that methylation profiles of HCC tumor DNA and matched plasma ctDNA are highly correlated. We constructed a diagnostic prediction model with high diagnostic specificity and sensitivity and was highly correlated with tumor burden, treatment response, and stage. Additionally, we constructed a prognostic prediction model that effectively predicted prognosis and survival. |