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SELECTBIO Conferences Lab-on-a-Chip, Microfluidics & Microarrays World Congress

Hsueh-Chia Chang's Biography



Hsueh-Chia Chang, Bayer Professor of Chemical and Biomolecular Engineering, University of Notre Dame, Interim Chief Technology Officer, Aopia Biosciences

Over 300 publications, with 18,000 citations and h index of 76. He has confounded a startup Aopia Biosciences in 2020 on purification of extracellular vesicles and currently serves as its interim CTO.

Hsueh-Chia Chang Image

Low-Cost Biochips with Integrated Membrane Pretreatment and Molecular Sensing Components

Tuesday, 29 September 2015 at 11:30

Add to Calendar ▼2015-09-29 11:30:002015-09-29 12:30:00Europe/LondonLow-Cost Biochips with Integrated Membrane Pretreatment and Molecular Sensing ComponentsLab-on-a-Chip, Microfluidics and Microarrays World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com

A new low-cost (<$1) disposable polymer biochip platform, with 3-D architecture to allow easy fluid/electrical/optical connection and with integrated gel and ion-selective membranes, will be reviewed. Electrically induced concentration and charge polarization across the ion-selective membrane is used to effect on-chip pumping, cell lysing,  analyte  filtration, concentration and separation,  redox agent-insensitive electrical sensing , shear-enhanced selectivity,  pH control, nanoparticle aggregation for colorimetric and plasmonic optical sensing etc. The modular designs of the membrane components allow dynamic large-volume manufacturing of different biochip designs.  A large dynamic range(fM to mM), short assay time (30 min) and high selectivity (single-mismatch) is reported for a particular turn-key RNA sensing device for contagious diseases. The cost, speed and automated multi-plex integration design allows detection of a small number of easily degradable nucleic acid targets in a portable device.


Add to Calendar ▼2015-09-28 00:00:002015-09-30 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarrays World CongressLab-on-a-Chip, Microfluidics and Microarrays World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com