Martyn Boutelle,
Professor of Biomedical Sensors Engineering,
Imperial College London
Martyn Boutelle is Professor of Biomedical Sensors Engineering in the Department of Bioengineering, Imperial College London, and Associate Provost for Estates Planning for Imperial College. His research group is multidisciplinary comprising, bioengineers, scientists, and clinicians. He develops novel analytical science methods using microfluidics, electrochemical sensors / biosensors, and wireless electronics to make portable (sometimes wearable) monitoring devices for use as point of care devices that typically giving continuous real -time displays. He then uses these in a program of clinical science research focusing on the acute traumatic brain injury including that caused by cardiac arrest, neonatal continuous monitoring and kidney transplantation monitoring. He runs the EPSRC funded Bio-nanofabrication suite designed to make microfluidic and biosensor biosensors using scalable methods to allow use in proof-of-concept clinical trials.
Martyn is past president of the International Society for Monitoring Molecules in Neuroscience, and a founder of the COSBID organization for studying acute human brain injury. He published > 190 papers, chapters and patents. He obtained a BSc and PhD in Chemistry from Imperial College and worked as an EP Abraham Research Fellow in the University of Oxford.
Next Generation Real-Time Clinical Monitoring Using Microfluidic Devices
Wednesday, 30 September 2015 at 14:00
Add to Calendar ▼2015-09-30 14:00:002015-09-30 15:00:00Europe/LondonNext Generation Real-Time Clinical Monitoring Using Microfluidic DevicesLab-on-a-Chip, Microfluidics and Microarrays World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Modern intensive care medicine seeks to protect vunerable tissue from damage by monitoring the pattern of changing physical, electrical and chemical changes taking place in tissue – multimodal monitoring. Microfluidic lab-on-chip devices coupled to microdialysis sampling probes provides a new way for measuring real-time chemical changes. The low volume flow rates (0.2 – 2 µL / min) of microdialysis probes are ideal for linking to microfluidic lab-on-chip analysis devices. Concentrations of key biomarker molecules can then be determined continuously using either electrochemically (using amperometric, and potentiometic sensors) or optically. Droplet-based microfluidics, by digitizing the dialysis stream into discrete low volume samples, (a) allows rapid concentration change to be detected without the effects of the temporal smearing caused by dispersion, and (b) allows dialysate droplets to be quickly transported from the patient or surgical field to the analysis chip. This talk will overview successful design, optimization, automatic-calibration and use of both droplet-based and continuous flow microfluidic analysis systems for real-time clinical monitoring. Examples will be taken from our recent work during reconstructive surgery and, extended monitoring of the traumatically injured brain in the intensive care unit.
Add to Calendar ▼2015-09-28 00:00:002015-09-30 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarrays World CongressLab-on-a-Chip, Microfluidics and Microarrays World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com