David Brooks,
Head of Clinical & Business Development,
TwistDx Ltd.
David is responsible for Clinical and Business Development at TwistDx. He has organized numerous infectious disease diagnostic clinical programmes and led external opportunity development at TwistDx.
Recombinase Polymerase Amplification (RPA): An Isothermal DNA Amplification Method Enabling Point-of-Care Microfluidic-based Diagnostics
Wednesday, 28 September 2016 at 13:30
Add to Calendar ▼2016-09-28 13:30:002016-09-28 14:30:00Europe/LondonRecombinase Polymerase Amplification (RPA): An Isothermal DNA Amplification Method Enabling Point-of-Care Microfluidic-based DiagnosticsSELECTBIOenquiries@selectbiosciences.com
RPA offers PCR equivalent specificity and sensitivity and lends itself to microfluidic application due to a low working temperature, rapid amplification, lyophilised reagents stored at ambient temperature, small reaction volumes, and multiple detection formats such as lateral flow, fluorescence, and electrochemistry. A number of users have successfully deployed RPA assays on to a range of microfluidic platforms such as quantitative digital, emulsion droplet, centrifugation, and using various read-out modalities. Assays for numerous targets have been developed such as for food pathogens, human IVDs, and GMO in food products. We will review some of these embodiments of microfluidic RPA usage that illustrate the potential of the biochemistry.
Add to Calendar ▼2016-09-26 00:00:002016-09-28 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics: Companies, Technologies and CommercializationSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2016-09-28 13:30:002016-09-28 14:30:00Europe/LondonRecombinase Polymerase Amplification (RPA): An Isothermal DNA Amplification Method Enabling Point-of-Care Microfluidic-based DiagnosticsSELECTBIOenquiries@selectbiosciences.com
