Paul Yager,
Professor, Department of Bioengineering,
University of Washington
Paul Yager is the Professor in the Department of Bioengineering at the University of Washington, Seattle. Professor Yager served as the The Hunter and Dorothy Simpson Endowed Chair, Department of Bioengineering from 2008-2013. Professor Yager's research focuses on microfluidics and its applications in global health.
Re-envisioning Point-of-Care Pathogen Diagnostics for the Developed and Developing Worlds
Monday, 2 October 2017 at 14:00
Add to Calendar ▼2017-10-02 14:00:002017-10-02 15:00:00Europe/LondonRe-envisioning Point-of-Care Pathogen Diagnostics for the Developed and Developing WorldsSELECTBIOenquiries@selectbiosciences.com
Whether the purpose is to guide treatment of an individual’s infection,
or to control the outbreak of a pandemic, there is an urgent need for
low-cost rapid diagnostic devices capable of identifying the cause of
infectious disease that free testing from the centralized laboratory.
“Ubiquitous diagnostics”, aided by the revolution that brought us
today’s distributed computing and communications, can bring the best
diagnostic capabilities to physicians’ office laboratories and
pharmacies in the developed world, or to places in the developing world
where nothing is available now. The practice of medicine itself can be
improved if diagnostic tests could be carried out more rapidly and
pervasively. The Yager lab has been engaged in a 20-year pursuit of
microfluidics-based tools and complete systems for pathogen
identification in human samples, most recently in an inexpensive
instrument-free single-use disposable format that could be used by
consumers in their homes and by healthcare workers in low-resource
settings in the developing world. The central effort today is to
utilize capillary action in porous materials to eliminate the need for
pumps and other equipment to control fluid flow. By coupling the
chemical testing with cell phones, critical health data can be analyzed
rapidly and anywhere, and the best healthcare decisions can be made for
patients, for regional healthcare systems, and for global health. There
have been 3 analytical approaches pursued in our group: Identification
and quantification of 1) antibodies specific to pathogens, 2) proteins
of the pathogens, and 3) nucleic acid sequences derived from the
pathogens. We report on recent results on particularly simple
paper-based systems supported by NIH (detection of influenza proteins;
improvement of specificity of Zika virus serology), DARPA (detection of
DNA and RNA from bacterial and viral pathogens) and DTRA (detection of
proteins from the Ebola virus). All projects involve close
collaboration with partners inside and outside the university
environment, and are aimed at producing clinically useful tools for
point-of-care medicine.
Add to Calendar ▼2017-10-02 00:00:002017-10-04 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics: Companies, Technologies and CommercializationSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2017-10-02 14:00:002017-10-02 15:00:00Europe/LondonRe-envisioning Point-of-Care Pathogen Diagnostics for the Developed and Developing WorldsSELECTBIOenquiries@selectbiosciences.com
