Dino Di Carlo's Biography

Dino Di Carlo, Armond and Elena Hairapetian Chair in Engineering and Medicine, Professor and Vice Chair of Bioengineering, University of California-Los Angeles

Dino Di Carlo received his B.S. in Bioengineering from the University of California, Berkeley in 2002 and received a Ph.D. in Bioengineering from the University of California, Berkeley and San Francisco in 2006. From 2006-2008 he conducted postdoctoral studies in the Center for Engineering in Medicine at Harvard Medical School. He has been on the faculty in the Department of Bioengineering at UCLA since 2008 and now as Professor of Bioengineering and Mechanical Engineering serves as the Vice Chair of the Department and as the director of the Cancer Nanotechnology Program in the Jonsson Comprehensive Cancer Center. His research pioneered the use of inertial fluid dynamic effects for the control, separation, and analysis of cells in microfluidic devices. His recent work extends into numerous other fields of biomedicine and biotechnology including directed evolution, cell analysis for rapid diagnostics, new amplified molecular assays, next generation biomaterials, and phenotypic drug screening. He has also been a leader in technology entrepreneurship: He co-founded and currently serves on the board of directors of five companies that are commercializing UCLA intellectual property developed in his lab (CytoVale, Vortex Biosciences, Tempo Therapeutics, Forcyte Biotechnologies and Ferrologix). Among other honors he received the Presidential Early Career Award for Scientists and Engineers (PECASE) and was elected a Fellow of the American Institute for Medical and Biological Engineering in 2016, was elected a Fellow of the Royal Society of Chemistry (FRSC) in 2014, was awarded the National Science Foundation (NSF) Faculty Early Career Development award and the U.S. Office of Naval Research (ONR) Young Investigator Award, the Packard Fellowship and Defense Advanced Research Projects Agency (DARPA) Young Faculty Award, and received the National Institutes of Health (NIH) Director’s New Innovator Award and Coulter Translational Research Award.

Accelerating Life Science Research: From Lab-on-a-Chip to Lab-on-a-Particle

Tuesday, 19 November 2024 at 09:00

Add to Calendar ▼2024-11-19 09:00:002024-11-19 10:00:00Europe/LondonAccelerating Life Science Research: From Lab-on-a-Chip to Lab-on-a-ParticleLab-on-a-Chip and Microfluidics World Congress 2024 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com

Building on the successes of Lab on a Chip technologies, a new frontier is emerging in the form of Lab on a Particle (LoP) platforms. These innovative technologies complement traditional microfluidic systems by utilizing microparticles to confine samples and facilitate microscale reactions. Unlike the static nature of microfluidic chips, LoP platforms offer dynamic and flexible solutions where microparticles act as discrete, suspendable compartments capable of performing highly parallelized assays. This advancement significantly enhances the ability to analyze molecules and cells with higher throughput, while incorporating sophisticated assays. The microparticles used in LoP assays are meticulously engineered with unique shapes and chemistries, providing functionalities that were previously unattainable with conventional microfluidic chips. These particles can template droplets, capture specific molecules, cells, and secretions, or even barcode reactions for multiplexed analysis. The integration of essential assay materials and structures directly into each particle eliminates the dependency on custom chips or specialized instrumentation. As a result, LoP platforms are compatible with standard laboratory instruments such as flow cytometers, fluorescence activated cell sorters (FACS), microscopes, and other imaging devices. This compatibility positions LoP technologies akin to software applications, or apps, operating on commonly available life science instrument hardware. This analogy highlights the transformative potential of LoP platforms in democratizing access to advanced assay capabilities. By circumventing the need for specialized equipment, these microparticle-based systems can accelerate adoption and broaden the impact of microfluidic innovations across diverse research fields. In this keynote presentation, we will explore some recent Lab on a Chip innovations developed in our lab, including Ferrobotics, and introduce recent Lab on a Particle platforms and applications. We will discuss demonstrated applications, such as in antibody discovery, elucidating links between cell secretions and gene expression, and identifying therapeutically optimal cells, ultimately highlighting the future prospects of LoP technologies in accelerating all life sciences.

Add to Calendar ▼2024-11-18 00:00:002024-11-20 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics World Congress 2024Lab-on-a-Chip and Microfluidics World Congress 2024 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com

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