Uwe Marx,
CSO & Founder,
TissUse GmbH, Honorary Professor for Medical Biotechnology at the Technische Universität Berlin, Germany
Trained in human biology and medicine, Dr. Marx is an accomplished serial entrepreneur and the scientific founder of TissUse. He is a renowned tissue engineer and pioneered a human multi-organ-bioreactor program in the early 1990´s. Since 2010 he is the head of the “Multi-Organ-Chip” program in the Institute of Biotechnology at the Technische Universität Berlin, Germany. Over the course of his fruitful career in biotechnology, Dr. Marx has pursued ever more lifelike structures that can mimic human biology in vitro, culminating in the multi-organ-chip platform. Prior to founding TissUse, Dr. Marx was the scientific founder of the two successful Germany-based biotech companies, ProBioGen AG and VITA34, the first private umbilical cord blood bank in Europe.
Design, Prototyping and Feasibility Studies for Pump-based Multi-Organ MPS
Monday, 24 October 2022 at 16:30
Add to Calendar ▼2022-10-24 16:30:002022-10-24 17:30:00Europe/LondonDesign, Prototyping and Feasibility Studies for Pump-based Multi-Organ MPSBioengineering for Building Microphysiological Systems 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Microfluidic microphysiological systems have proven to be a powerful tool for recreating human tissue- and organ-like functions at research level. This provides the basis for the establishment of qualified preclinical assays with improved predictive power. However, industrial adoption of MPS-based assays is progressing slowly due to their complexity. The presentation focusses on the design and prototyping principles of the microfluidic HUMIMIC® platform integrating on-chip micro-pumps and capable to maintain functional various human organ model combinations or single organ equivalents over weeks. Challenges of industrial adoption of the platform, with the focus on models supporting repeated dose testing will be discussed. The creation of complex physiology-based autologous multi-organ systems, mimicking adsorption, distribution, metabolism, excretion and crucial organismal feedback loops will be pointed out. Feasibility study data will be presented.
Add to Calendar ▼2022-10-24 00:00:002022-10-25 00:00:00Europe/LondonBioengineering for Building Microphysiological Systems 2022Bioengineering for Building Microphysiological Systems 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2022-10-24 16:30:002022-10-24 17:30:00Europe/LondonDesign, Prototyping and Feasibility Studies for Pump-based Multi-Organ MPSBioengineering for Building Microphysiological Systems 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
