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Extending the Capabilities of Flow Cytometry by Advances in Sensitivity and Resolution

Tuesday, 29 September 2015 at 14:30

Add to Calendar ▼2015-09-29 14:30:002015-09-29 15:30:00Europe/LondonExtending the Capabilities of Flow Cytometry by Advances in Sensitivity and ResolutionNGS, SCA, Mass Spec: The Road to Diagnostics in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com

Driven by the need to understand complex cell systems, high performance instruments and new reagents and assays are pushing the boundaries of the current generation of commercial systems. Multiparameter cell measurement using fluorescent probes can exceed 20 colors, while mass spec-based cytometry (mass cytometry) pushing beyond 50 parameters. Optical detection, which is desired for many applications, including single cell sorting, is being extended by spectral flow cytometry, where high spectral resolution enables the use of new analysis methods, optical probes, and multiplexing approaches. Higher sensitivity instruments and brighter reagents are allowing single particle analysis to extend to the nanoscale, to study complex systems of extracellular vesicles that mediate communication between cells and through the organism.  This presentation will focus on these new instruments, reagents and assays, and the biomedical applications they are enabling in cardiovascular disease, cancer, and other areas.