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SELECTBIO Conferences NGS, SCA, Mass Spec: The Road to Diagnostics

Gary Siuzdak's Biography



Gary Siuzdak, Professor and Director, The Scripps Research Institute

Gary Siuzdak is Director of the Scripps Center for Metabolomics and Professor of Chemistry, Molecular and Computational Biology at The Scripps Research Institute in La Jolla, California (http://masspec.scripps.edu/). He has served as Vice President of the American Society for Mass Spectrometry. His research includes developing novel mass spectrometry-based approaches in metabolomics, nanostructure-based imaging, microorganism analysis, and enzyme activity assays. He has over 200 peer-reviewed publications and two books, "Mass Spectrometry for Biotechnology" and the "The Expanding Role of Mass Spectrometry in Biotechnology", 2006 Edition.

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Mass Spectrometry-Based Metabolomics as a Unique Biochemical Approach for Understanding Disease Pathogenesis

Wednesday, 30 September 2015 at 14:30

Add to Calendar ▼2015-09-30 14:30:002015-09-30 15:30:00Europe/LondonMass Spectrometry-Based Metabolomics as a Unique Biochemical Approach for Understanding Disease PathogenesisNGS, SCA, Mass Spec: The Road to Diagnostics in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com

Metabolomics, the quantitative global analysis of endogenous metabolites from cells, tissues, fluids and whole organisms, is becoming an integral part of functional genomics efforts as well as a tool for understanding fundamental biochemistry. While the genome and proteome represent upstream biochemical events, metabolites correlate with the most downstream biochemistry and therefore most closely represent the phenotype.  This has been proven by the broad success of metabolite analysis in clinical diagnostics. The experimental aim in our studies is to obtain a comprehensive quantitative view of the metabolome to expand our understanding of what pathways are altered in specific diseases. We have developed a novel mass spectrometry platform for metabolomics including XCMS Online data analysis combined with METLIN, a comprehensive MS/MS metabolite database. These technologies will be presented in the context of their application to disease.


Add to Calendar ▼2015-09-28 00:00:002015-09-30 00:00:00Europe/LondonNGS, SCA, Mass Spec: The Road to DiagnosticsNGS, SCA, Mass Spec: The Road to Diagnostics in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com