Jennifer Lewis,
Professor,
Harvard University School of Engineering and Applied Sciences
Jennifer A. Lewis recently joined the faculty of the School of Engineering and Applied Sciences and the Wyss Institute for Biologically Inspired Engineering at Harvard University. An innovative pioneer in 3D printing, she leads a vibrant research group that creates new materials and printing platforms for fabricating functional devices and vascularized tissues. She is a Fellow of American Academy of Arts and Sciences, Materials Research Society, the American Physical Society, and the American Ceramic Society. She has received several awards, most notably the MRS Medal, the ACS Langmuir Lecture Award, and the NSF Presidential Faculty Fellow Award. She has published 130 papers, holds 8 patents, and has founded two companies to commercialize the technologies developed in her lab.
The advancement of tissue and, ultimately, organ engineering requires the ability to pattern human tissues composed of cells, extracellular matrix, and vasculature with controlled microenvironments that can be sustained over prolonged time periods. To date, bioprinting methods have yielded thin tissues that only survive for short durations. To improve their physiological relevance, we report a method for bioprinting 3D tissues on perfusable chips. Specifically, we will describe the bioprinting of thick vascularized, stem-cell laden tissues that can be controllably perfused and differentiated along an osteogenic lineage on chip. We will then describe how this approach can be extended to create other functional tissue constructs, such as 3D proximal tubules, on chip for drug screening. Our approach combines bioprinting, 3D cell culture, and tissue-on-chip concepts opening new avenues for drug screening, disease models, and ultimately tissue repair and regeneration.
Add to Calendar ▼2016-07-07 00:00:002016-07-08 00:00:00Europe/LondonOrgan-on-a-Chip World Congress and 3D-Culture 2016Organ-on-a-Chip World Congress and 3D-Culture 2016 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com
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