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SELECTBIO Conferences Organ-on-a-Chip and 3D-Culture: Companies, Technologies and Approaches
Conferences  \  Organ-on-a-Chip World Congress & 3D-Culture 2017  \  Organ-on-a-Chip and 3D-Culture: Companies, Technologies and Approaches  \  Agenda  \  Holger Becker
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Holger Becker's Biography


Holger Becker, Chief Scientific Officer, Microfluidic ChipShop GmbH

Dr. Holger Becker is co-founder and CSO of microfluidic ChipShop GmbH. He obtained physics degrees from the University of Western Australia/Perth and the University of Heidelberg. He started to work on miniaturized systems for chemical analysis during his PhD-thesis at Heidelberg university, where he obtained his PhD in 1995. Between 1995 and 1997 he was a Research Associate at Imperial College with Prof. Andreas Manz. In 1998 he joined Jenoptik Mikrotechnik GmbH. Since then, he founded and led several companies in the field of microsystem technologies in medicine and the life sciences. He lead the Industry Group of the German Physical Society between 2004 and 2009 and is Conference Chair for the SPIE "Microfluidics, BioMEMS and Medical Microsystems" conference as well as acting as regular reviewer of project proposals on national and EU level and for several journals devoted to microsystem technologies.

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Microfluidic Organ-on-a-Chip Devices for Stem-Cell Cultivation, Differentiation and Toxicity Testing

Monday, 10 July 2017 at 16:30

Add to Calendar ▼2017-07-10 16:30:002017-07-10 17:30:00Europe/LondonMicrofluidic Organ-on-a-Chip Devices for Stem-Cell Cultivation, Differentiation and Toxicity TestingSELECTBIOenquiries@selectbiosciences.com

We have developed diagnostic multi-organ microfluidic chips based on patient specific induced pluripotent stem cell (iPS) technology to explore liver dependent toxic effects of drugs on individual human tissues such as liver or kidney cells. Based initially on standardized microfluidic modules for cell culture, we have developed integrated microfluidic devices which contain different chambers for cell/tissue cultivation as well as on-chip cell-culture medium actuation with an on-board peristaltic pump and gas exchange using integrated membranes. The devices are manufactured using industrial manufacturing methods. In the project, suitable surface modification methods of the used materials as well as hybrid integration of different elements had to be explored. We have been able to successfully demonstrate the seeding, cultivation and further differentiation of modified iPS, as shown by the use of differentiation markers, thus providing a suitable platform for toxicity testing and potential tissue-tissue interactions.

Add to Calendar ▼2017-07-10 00:00:002017-07-11 00:00:00Europe/LondonOrgan-on-a-Chip and 3D-Culture: Companies, Technologies and ApproachesSELECTBIOenquiries@selectbiosciences.com


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