Can Multi-Organ Chips Be Used for Drug Development Studies?Wednesday, 8 July 2015 at 10:00 Add to Calendar ▼SELECTBIOenquiries@selectbiosciences.com Effective human surrogates, created from combining human tissue engineered constructs with microfabricated systems, could have a major impact on drug development, particularly in making better decisions on which drugs to take into human clinical trials. Early prediction of human response would be crucial to such decisions. Our designs are guided by physiologically based pharmacokinetic models. We will describe possible approaches to use “pumpless”, low cost platforms to build such human surrogates for evaluation of potential response to drugs. Can Multi-Organ Chips Be Used for Drug Development Studies?Wednesday, 8 July 2015 at 10:00 Add to Calendar ▼SELECTBIOenquiries@selectbiosciences.com Effective human surrogates, created from combining human tissue engineered constructs with microfabricated systems, could have a major impact on drug development, particularly in making better decisions on which drugs to take into human clinical trials. Early prediction of human response would be crucial to such decisions. Our designs are guided by physiologically based pharmacokinetic models. We will describe possible approaches to use “pumpless”, low cost platforms to build such human surrogates for evaluation of potential response to drugs. |