Roger Kamm,
Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering,
Massachusetts Institute of Technology (MIT)
Kamm is currently the Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering at MIT, where he has served on the faculty since 1978. Kamm has long been instrumental in developing research activities at the interface of biology and mechanics, formerly in cell and molecular mechanics, and now in engineered living systems. Current interests are in developing models of healthy and diseased organ function using microfluidic technologies, with a focus on vascularization, metastatic cancer and neurological disease. Kamm has fostered biomechanics as Chair of the US National Committee on Biomechanics (2006-2009) and of the World Council on Biomechanics (2006-2010). For 10 years, he was Director of the NSF Science and Technology Center on Emergent Behaviors of Integrated Cellular Systems. He is the 2010 recipient of the ASME Lissner Medal and the 2015 recipient of the Huiskes Medal, both for lifetime achievements, and was the inaugural recipient of the ASME Nerem Medal for mentoring and education. He was elected to the National Academy of Medicine in 2010 and Engineering in 2022. Kamm is co-founder of AIM Biotech, a manufacturer of microfluidic systems for 3D culture.
A vascular network is an essential part of most organs in vivo, so it is natural that in vitro organ models also be vascularized. Yet, developing a vascular system on a chip, especially the microvessels, generally presents one of the greatest engineering challenges. In recent years, several groups have either engineered vascular networks, or induced them to grow within their in vitro systems. These are comprised either of a formed channel lined with endothelial cells, a network that grows within a formed hydrogel, or a combination of the two. Models of this type have been employed to simulate metastatic cancel or to mimic certain aspects of organ function such as the blood brain barrier. In this talk, I will review the current state-of-the-art and propose ways forward in obtaining vascularized models of dense, cellular tissues.
Add to Calendar ▼2015-07-08 00:00:002015-07-09 00:00:00Europe/LondonOrgan-on-a-Chip World Congress and 3D-PrintingOrgan-on-a-Chip World Congress and 3D-Printing in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com
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