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SELECTBIO Conferences 3D-Culture & Organoids 2019

Gary Gintant's Biography



Gary Gintant, Senior Research Fellow, Abbvie

Dr. Gary Gintant is Senior Research Fellow in the Dept. of Integrative Pharmacology, Integrated Science and Technology, at AbbVie. He is involved in multiple internal drug discovery and safety initiatives internally; external activities include various cardiac safety initiatives (such as ILSI/HESI Proarrhythmia Models Project, the Cardiac Safety Research Consortium, and the Comprehensive in Vitro Proarrhythmia Assay Initiative) while serving on various journal editorial boards, NIH study sections, and Safety Pharmacology Society committees. Research interests include cardiovascular pharmacology, cellular electrophysiology/ion channels, arrhythmias, application of stem-cell derived cells and tissues to drug discovery efforts, and translational medicine. He gained his MA, M.Phil. and PhD degrees from the College of Physicians and Surgeons of Columbia University.

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In vitro Safety Assays with Human-Derived Cardiomyocytes… Bridging the Translational Gaps?

Tuesday, 15 October 2019 at 09:00

Add to Calendar ▼2019-10-15 09:00:002019-10-15 10:00:00Europe/LondonIn vitro Safety Assays with Human-Derived Cardiomyocytes… Bridging the Translational Gaps?3D-Culture and Organoids 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com

In vitro studies with human derived cardiomyocytes are increasingly being used for cardiovascular safety evaluations in candidate drug selection as well as regulatory assessments.  How well these models perform depend on level of recapitulation of the cardiac biology present in the experimental models as well as the questions being addressed and parameters being measured.  While the biology is critical, the successful use of these models to bridge the translational gaps between in vitro cardiomyocyte studies and clinical studies requires considering more than the cardiac biology.


Add to Calendar ▼2019-10-14 00:00:002019-10-15 00:00:00Europe/London3D-Culture and Organoids 20193D-Culture and Organoids 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com