Anand Giddabasappa,
Principal Scientist, Global Science and Technology,
Pfizer
He is a Principal Scientist at Global Science and Technology, Worldwide Comparative medicine, Pfizer Inc, San Diego, CA. Currently, he leads a team that develops pre-clinical in vivo animal models and imaging techniques for oncology drug discovery. His other areas of expertise includes ophthalmology, inflammation and vaccines. Anand received his PhD from University of Houston and MS degree from NIPER (India).
Biodistribution of Antibody-based Drugs Using in vivo Fluorescence Imaging as a Biomarker
Friday, 16 January 2015 at 15:30
Add to Calendar ▼2015-01-16 15:30:002015-01-16 16:30:00Europe/LondonBiodistribution of Antibody-based Drugs Using in vivo Fluorescence Imaging as a BiomarkerPrognostic, Predictive, and POC: Biomarkers from Research to Clinic in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Currently, biodistribution of small molecules and biologics are evaluated by PET imaging, autoradiography or pharmacokinetic studies. PET and autoradiography use radiological reagents which need special facilities or a CRO and also have limited shelf life due to radioactive decay. Conversely, the PK methods are terminal, require large number of animals and evaluation of whole body biodistribution is not easily done due to technical difficulties. Recent developments in optical imaging probes and technologies have given us an opportunity to evaluate biodistribution and targeting of biologic drugs without use of radio-labeled materials. In this presentation I will be discussing the opportunities and challenges of in vivo fluorescence imaging in biodistribution of antibody based drugs.
Add to Calendar ▼2015-01-15 00:00:002015-01-16 00:00:00Europe/LondonPrognostic, Predictive, and POC: Biomarkers from Research to ClinicPrognostic, Predictive, and POC: Biomarkers from Research to Clinic in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2015-01-16 15:30:002015-01-16 16:30:00Europe/LondonBiodistribution of Antibody-based Drugs Using in vivo Fluorescence Imaging as a BiomarkerPrognostic, Predictive, and POC: Biomarkers from Research to Clinic in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
