Silicon Photonic Point-of-Care Sensors for Multiplexed DiagnosticsFriday, 19 September 2014 at 14:30 Add to Calendar ▼2014-09-19 14:30:002014-09-19 15:30:00Europe/LondonSilicon Photonic Point-of-Care Sensors for Multiplexed DiagnosticsPoint-of-Care Diagnostics World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com The concept of personalized medicine is predicated on an ability to comprehend a patient’s disease state in a highly informed manner that ideally illuminates an effective, molecularly-targeted treatment strategy. A growing body of evidence suggests that the simultaneous measurement of many unique biomolecular signatures from a single clinically relevant sample would be incredibly enabling in achieving such an informative diagnosis. Unfortunately, this is an analytical feat that currently not possible using established methods, thereby limiting the implementation of informative molecular diagnostic and theragnostic strategies in the clinical treatment of disease. In response to this and other bioanalytical challenges that simultaneously require high sensitivity, high level multiplexing capability, and scalable and cost effective sensor fabrication, our group has developed a new biomolecular analysis platform based upon silicon photonic microring resonators. This detection strategy leverages well validated semiconductor fabrication, laser sources from optic telecommunications, and conventional microarraying tools to create highly multiplexed and robust biosensor arrays that are extraordinarily sensitive to biomolecular binding events at the sensor surface. In this talk I will describe our efforts to develop this emerging platform in the context of creating multiplexed detection solutions for point-of-care diagnostics. |