Marya Lieberman,
Professor,
University of Notre Dame
Dr. Marya Lieberman is a surface and analytical chemist with over 60 peer-reviewed papers in the area of molecular electronics, DNA nanostructures, and low-tech analytical methods. She studied chemistry at MIT, obtained her doctorate in inorganic chemistry at the University of Washington, Seattle, and was a postdoc at the California Institute of Technology. Her current research focuses on paper millifluidic devices for chemical analysis in low-resource settings. These robust, inexpensive, and easy-to-use test cards help people solve problems outside the laboratory. Applications include detection of falsified and substandard medicines, monitoring nutritional supplement quality and population nutrition status, presumptive identification of illicit drugs, and evaluation of toxins in the environment.
Design for Point-of-Need Testing in the Developing World
Tuesday, 29 September 2015 at 14:30
Add to Calendar ▼2015-09-29 14:30:002015-09-29 15:30:00Europe/LondonDesign for Point-of-Need Testing in the Developing WorldPoint-of-Care Diagnostics and Global Health World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
This talk will focus on design of paper millifluidic devices for chemical analysis outside a laboratory setting. The main analytical applications that our group has pursued are detection of low quality or fake pharmaceuticals and quantitative analysis of the iodine content of iodized salt. Paper test cards for analysis of five antibiotics (ampicillin, amoxicillin, amoxicillin/clavulanate, azithromycin, and ciprofloxacin) are being implemented in the pharmacovigilance system of the second largest hospital in Kenya, and a titration-on-paper card is undergoing external validation studies and technology comparison studies at labs in South Africa and Burkina Faso. Because academic researchers in the developed world are sometimes frustrated when they attempt to translate laboratory prototypes to field studies in the developing world, this talk will focus on design features that made the test cards more acceptable for users in the developing world. Key design elements included bringing researchers to the field setting to better understand user constraints , maintaining connections to users; selection of analytical targets that our users think are most important; using cell phones to read card results, which makes the devices easier to use; and a life-cycle approach that maximizes ease of manufacture and minimizes the hazard and environmental impact of the cards. The resulting point-of-need devices balance sensitivity, selectivity, and robustness in order to meet the user's analytical goals in a field setting where instruments, electricity, reagents, and laboratory equipment are often not available.
Add to Calendar ▼2015-09-28 00:00:002015-09-30 00:00:00Europe/LondonPoint-of-Care Diagnostics and Global Health World CongressPoint-of-Care Diagnostics and Global Health World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2015-09-29 14:30:002015-09-29 15:30:00Europe/LondonDesign for Point-of-Need Testing in the Developing WorldPoint-of-Care Diagnostics and Global Health World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
