Viability Screens with Pooled shRNA Libraries Identify Novel and Synthetically Lethal Anti-Cancer TargetsThursday, 19 April 2012 at 14:15 Add to Calendar ▼2012-04-19 14:15:002012-04-19 15:15:00Europe/LondonViability Screens with Pooled shRNA Libraries Identify Novel and Synthetically Lethal Anti-Cancer TargetsSELECTBIOenquiries@selectbiosciences.com We identified and confirmed hundreds of genes modulating proliferation and survival in oncogenic cells using pooled lentiviral shRNA libraries. Also, we adapted and executed an approach to combinatorially screen shRNA to discover additive and synergistic combinations that are synthetically lethal. |