MiR-149 Targets Caspase-2 to Promote Glioma Cell Growth in vitro & in vivoThursday, 19 April 2012 at 10:00 Add to Calendar ▼2012-04-19 10:00:002012-04-19 11:00:00Europe/LondonMiR-149 Targets Caspase-2 to Promote Glioma Cell Growth in vitro and in vivoSELECTBIOenquiries@selectbiosciences.com MiR-149 binds to the 3'UTR of caspase-2 to down-regulate caspase-2 expression. Caspase-2 may impair glioma cells growth. Overexpressed miR-149 in U87 glioma cells xenografted in nude mice resulted in significant tumor growth by targeting caspase-2. |