Sai Kiang Lim's Biography

Sai Kiang Lim, Research Director, Institute of Medical Biology, A*STAR

Dr Sai-Kiang Lim graduated with B.Sc (Hons), NUS. PhD SUNY at Buffalo and did post-doctoral training Columbia University. She led independent research groups at NUMI, NUS (1996-2001), Genome Institute of Singapore (2002-2007) and then Institute of Medical Biology (2007-present). The current research interest in her lab is the study of extracellular vesicles (EVs) for the development of therapeutics and diagnostics as well as artificial lipid membrane vesicles.

Immunomodulatory MSC Exosome and Small Extracellular Vesicles

Monday, 9 September 2019 at 10:00

Add to Calendar ▼2019-09-09 10:00:002019-09-09 11:00:00Europe/LondonImmunomodulatory MSC Exosome and Small Extracellular VesiclesCirculating Biomarkers, Exosomes and Liquid Biopsy Asia 2019 in Seoul, KoreaSeoul, KoreaSELECTBIOenquiries@selectbiosciences.com

Mesenchymal stromal cell (MSC) are the most clinically tested cell type for regenerative medicine. Despite much setbacks, MSC is now gaining traction as a safe. viable regenerative medicine with recent market approval for use in GVHD and Crohn’s disease. However, it is increasingly clear that small extracellular vesicles (sEVs) of 50 to 200 nm diameter such as exosomes mediate the therapeutic potency of MSCs. Since the first demonstration that MSC secretes cardioprotective sEVs in a mouse and pig models of myocardial ischemia/reperfusion injury, these sEVs were widely reported to therapeutically efficacious against at least 30 other indications. A common observation in many MSC sEV-mediated efficacies is a significant immunomodulatory effect. This talk will describe our studies on the immunomodulatory potential of MSC sEVs.

Add to Calendar ▼2019-09-09 00:00:002019-09-10 00:00:00Europe/LondonCirculating Biomarkers, Exosomes and Liquid Biopsy Asia 2019Circulating Biomarkers, Exosomes and Liquid Biopsy Asia 2019 in Seoul, KoreaSeoul, KoreaSELECTBIOenquiries@selectbiosciences.com

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