Chwee Teck Lim,
NUS Society Chair Professor, Department of Biomedical Engineering, Institute for Health Innovation & Technology (iHealthtech), Mechanobiology Institute,
National University of Singapore
Professor Chwee Teck LIM is the NUSS Chair Professor and Director of the Institute for Health Innovation and Technology at the National University of Singapore. He has coauthored over 500 journal publications and cofounded six startups with one public listed in 2018. Prof Lim is an elected Fellow of nine academies and organizations including the Royal Society UK, US National Academy of Inventors, IUPESM, AIMBE, IAMBE, Singapore National Academy of Science and Academy of Engineering Singapore. He has garnered numerous research awards including Nature Lifetime Achievement Award for Mentoring in Science, Highly Cited Researcher, Asia’s Most Influential Scientist Award, Wall Street Journal Asian Innovation Award (Gold) and the President's Technology Award.
Microfluidics Technologies for Cancer Diagnosis - From Cell Capture to Single Cell Analysis
Monday, 9 September 2019 at 11:15
Add to Calendar ▼2019-09-09 11:15:002019-09-09 12:15:00Europe/LondonMicrofluidics Technologies for Cancer Diagnosis - From Cell Capture to Single Cell AnalysisCirculating Biomarkers, Exosomes and Liquid Biopsy Asia 2019 in Seoul, KoreaSeoul, KoreaSELECTBIOenquiries@selectbiosciences.com
The presence of Circulating Tumor Cells (CTCs) in bloodstream of patients is an important intermediate step in cancer metastasis and can provide valuable insights into disease detection and personalized treatment. As compared to obtaining a tissue biopsy which is invasive and painful, ‘‘liquid biopsy’’ for CTCs detection can be easily performed via a routine blood draw. The presence and number of CTCs in peripheral blood has been associated with the severity of the disease and have potential uses for early detection, diagnosis, prognosis and treatment monitoring. However, the presence of the large number of blood cells complicates as well as makes detection of rare CTCs in blood of cancer patients extremely challenging. Here, we address these issues and demonstrate that physical biomarkers such as the unique size and deformability of CTCs can be effectively used for their detection and separation from blood via microfluidics. We do this by leveraging on the many inherent advantages of microfluidics such as high sensitivity and spatial resolution, short processing time and low device cost. We developed a suite of microfluidic biochips that exploit the principles of cell size/deformability based separation as well as inertial focusing to perform high throughput continuous detection and separation of diseased cells. These simple, efficient and cost effective microfluidic platforms will be invaluable in extracting viable CTCs for many downstream clinical applications including single cell analysis as well as personalized treatment.
Add to Calendar ▼2019-09-09 00:00:002019-09-10 00:00:00Europe/LondonCirculating Biomarkers, Exosomes and Liquid Biopsy Asia 2019Circulating Biomarkers, Exosomes and Liquid Biopsy Asia 2019 in Seoul, KoreaSeoul, KoreaSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2019-09-09 11:15:002019-09-09 12:15:00Europe/LondonMicrofluidics Technologies for Cancer Diagnosis - From Cell Capture to Single Cell AnalysisCirculating Biomarkers, Exosomes and Liquid Biopsy Asia 2019 in Seoul, KoreaSeoul, KoreaSELECTBIOenquiries@selectbiosciences.com
