A Platform for Detecting Tumor-Derived ExosomesTuesday, 2 October 2018 at 09:30 Add to Calendar ▼2018-10-02 09:30:002018-10-02 10:30:00Europe/LondonA Platform for Detecting Tumor-Derived ExosomesSingle Cell Analysis Summit 2018 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com Late-stage lung-cancer diagnosis is the major contributor to the poor survival of lung cancer patients. The lack of symptoms specific to early-stage lung cancer and the low sensitivity and high cost of current screening methods, are current barriers to early diagnosis. To address this challenge and enable rapid, cost-effective lung cancer screening, we are developing a microfluidic platform to detect tumor-derived exosomes in saliva. Our detection method utilizes resistive-pulse sensing to measure the size change of a micron-sized antibody-coated colloid when tumor-derived exosomes bind to it. Microscale in size, our platform can easily be manufactured using standard lithographic techniques. In this talk, I will describe our platform and the results we have achieved thus far to demonstrate its utility toward detecting tumor-derived exosomes for earl-stage detection of lung cancer. |