34 Parameter Single-Cell Mass Cytometry Delineates Clinically and Mechanistically Relevant Leukemic Differentiation SubstructuresThursday, 29 September 2011 at 09:00 Add to Calendar ▼2011-09-29 09:00:002011-09-29 10:00:00Europe/London34 Parameter Single-Cell Mass Cytometry Delineates Clinically and Mechanistically Relevant Leukemic Differentiation Substructures Single Cell Analysis Summit in San Francisco, USASan Francisco, USASELECTBIOenquiries@selectbiosciences.com Single-cell ‘mass cytometry’ was used to index surface and cytokine or drug responsive of kinase targets with 34 parameter analysis in 10s of millions of healthy human blood and bone marrow cells. In leukemias we identified multiple anomalous differentiation states and drug reactivities in presumably “heterogeneous” tumours, thus defining novel hierarchies in tumors that could be subjected to differential clinical outcomes and novel treatment regimens. |