Mikael Kubista's Biography

Mikael Kubista, Professor/Founder, TATAA Biocenter AB

Dr Kubista is founder and CEO of the TATAA Biocenters (www.tataa.com) and he is also head of the department of gene expression at the institute of Biotechnology of the Czech Academy of Sciences. He was one of the pioneers contributing to the development of quantitative real-time PCR (qPCR) and introduced qPCR for single cell expression profiling. He led the development of reagents for high throughput expression profiling at his team develop qPCR tomography for intracellular expression profiling. Most recently Kubista co-developed ValidPrime.

Taking Single Cell Profiling to New Dimensions

Wednesday, 16 March 2016 at 11:30

Add to Calendar ▼2016-03-16 14:15:002016-03-16 15:15:00Europe/LondonDay Two Afternoon SessionSingle Molecule and Single Cell Analysis in Madrid, SpainMadrid, SpainSELECTBIOenquiries@selectbiosciences.com

In the first part of my talk I will describe high throughput single cell profiling with focus on the experimental workflow and analysis of data, exemplifying with the profiling of individual astrocytes from mouse brains reflecting response to trauma. I will also present multiway studies, where expression of many genes in different types of samples/cells are measured over time and how most valuable information about the molecular processes involved and expression pathways can be extracted with powerful multivariate tools such as dynamic PCA available in GenEx. Finally, I will present qPCR tomography to measure intracellular mRNA and microRNA profiles in individual cells, providing new information about the mechanism underlying asymmetric cell division.

Day Two Afternoon Session

Wednesday, 16 March 2016 at 14:15

Add to Calendar ▼2016-03-15 00:00:002016-03-16 00:00:00Europe/LondonSingle Molecule and Single Cell AnalysisSingle Molecule and Single Cell Analysis in Madrid, SpainMadrid, SpainSELECTBIOenquiries@selectbiosciences.com

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