Shopping Cart (0)
My Account

Shopping Cart
SELECTBIO Conferences ADME & Predictive Toxicology Europe

Christopher Goldring's Biography



Christopher Goldring, Senior Lecturer, University of Liverpool

B.Sc. Biochemistry, Liverpool John Moores University, 1986; Ph.D. Biochemistry, Guy’s Hospital, London, 1991; PGCert in Learning and Tecahing, University of Liverpool, 2011; Wellcome Trust Travelling Research Scholar to Xi’an University, China, 1988-1989, Erasmus Visiting Scholar at the University of Siena, Italy, 1991. Previously carried out research and lectured at the Ecole Pratique des Hautes Etudes, University of Bourgogne, France and the Department of Nephrology, Bern University Hospital, Switzerland, before moving to The Drug Safety Group at the University of Liverpool, in 1999. He now leads the molecular and cellular toxicology group within the MRC Centre for Drug Safety Science (CDSS) (http://www.liv.ac.uk/drug-safety/) a leading UK centre led from the University of Liverpool, with a critical mass of scientists studying mechanisms of adverse reactions to drugs, and which is the coordinator of the new Mechanism based Improved Prediction of Drug-Induced Liver Injury (MIP-DILI) IMI programme. CG has nearly twenty years of experience of molecular bioanalysis, working with cell culture and in vivo models, and has largely focused on understanding transcriptional control in the liver. He has >60 journal and conference papers published to date. He has current MRC, Wellcome Trust, BBSRC, and Stem Cells for Safer Medicines support. He has been a panel member of Biotech grant committees for Enterprise Ireland, and he leads teaching programmes on Safety Pharmacology and Stem Cells in the Innovative Medicines Initiative Safescimet training programme. 

Christopher Goldring Image

The Role of Defence and Adaptation in Drug-Mediated Liver Toxicity

Tuesday, 13 March 2012 at 11:15

Add to Calendar ▼2012-03-13 11:15:002012-03-13 12:15:00Europe/LondonThe Role of Defence and Adaptation in Drug-Mediated Liver ToxicityADME and Predictive Toxicology Europe in Munich, GermanyMunich, GermanySELECTBIOenquiries@selectbiosciences.com

Chemical stress is a potentially deleterious state induced by exposure of cells to non-physiological levels of chemically reactive species (CRS) and it can play a role in off-target adverse drug reactions (ADRs). Whilst we are beginning to understand some of the key events that influence how the liver adapts to exposure to chemicals, we are still some distance from understanding how this actually pertains to Man. This talk will review the field and highlight key recent developments and the most significant challenges to our understanding as to whether defence and adaptation influences individual susceptibility.


Add to Calendar ▼2012-03-13 00:00:002012-03-14 00:00:00Europe/LondonADME and Predictive Toxicology EuropeADME and Predictive Toxicology Europe in Munich, GermanyMunich, GermanySELECTBIOenquiries@selectbiosciences.com