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SELECTBIO Conferences ADME & Predictive Toxicology

Hugo Kubinyi's Biography



Hugo Kubinyi, Retired Professor, BASF SE & University of Heidelberg

Hugo Kubinyi studied chemistry in Vienna, Austria. After his Ph.D. thesis at
the Max Planck Institute of Biochemistry in Munich he continued as a PostDoc
at the German Cancer Research Centre in Heidelberg. In 1966 he joined Knoll AG,
later a subsidiary of BASF AG. Development of a partial synthetic cardiac
glycoside (Meproscillarin, CLIFT; launched 1978).
In 1985 he moved to BASF AG. Since 1987, until his retirement in summer 2001,
he was responsible for the Molecular Modelling, X-ray Crystallography and Drug
Design group of BASF, since early 1998 also for Combinatorial Chemistry in the
Life Sciences.
In 1986 he was appointed as associate Professor of Pharmaceutical Chemistry
at the University of Heidelberg. He is former Chair of the Cheminformatics and
QSAR Society (1995-2000; from 2000-2007 Advisor to the Chair) and IUPAC Fellow.
In 2006 he received the Herman Skolnik Award (CINF, ACS) and in 2008 the
Nauta Award in Pharmacochemistry (EFMC) and the Nauta Chair (Vrije Universiteit,
Amsterdam).
From his scientific work resulted more than 100 publications and seven books
on QSAR, 3D QSAR, Drug Design Design (the German book "Wirkstoffdesign"
received the 1999 Book Award of the FCI, Association of Chemical Industry),
Chemogenomics in Drug Discovery, and Drug Discovery Technologies (Volume 3
of Comprehensive Medicinal Chemistry II, 2006).
He is a member of several Scientific Advisory Boards, coeditor of the Wiley-VCH
book series "Methods and Principles in Medicinal Chemistry", and member of the
Editorial Boards of several scientific journals.

Hugo Kubinyi Image

ADME and Toxicity - Problems in Prediction

Wednesday, 19 February 2014 at 09:00

Add to Calendar ▼2014-02-19 09:00:002014-02-19 10:00:00Europe/LondonADME and Toxicity - Problems in PredictionADME and Predictive Toxicology in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com

Whereas absorption depends on physicochemical properties and on various drug transporters, bioavailability and toxicity additionally depend on the rate and direction of metabolic degradation of a drug. The presentation will review some problems and the consequences for quantitative ADMET prediction.


Add to Calendar ▼2014-02-18 00:00:002014-02-19 00:00:00Europe/LondonADME and Predictive ToxicologyADME and Predictive Toxicology in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com