An Improved Testing Strategy for the Prediction of Drug Induced Liver InjuryWednesday, 19 February 2014 at 16:15 Add to Calendar ▼2014-02-19 16:15:002014-02-19 17:15:00Europe/LondonAn Improved Testing Strategy for the Prediction of Drug Induced Liver InjuryADME and Predictive Toxicology in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com Drug-induced liver injury (DILI) is a leading cause of drug failures in clinical trials and a top reason for drug withdrawals after approval. Consequently, reliable prediction of DILI at an early drug discovery stage will reduce potential failures in subsequent drug development programs. In my presentation I will describe an integration of enabling technologies (High Content Screening, toxicogenomics and advanced cell culture methodologies) with advanced bioinformatics/QSAR models to improve prediction for risk of DILI at early stages of drug discovery at lower experimental costs. |