| Conferences \ European Lab Automation \ Advances in Protein Crystallography \ Agenda \ Markus Gruetter |
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Chaperone-Assisted Crystallography with DARPinsThursday, 30 June 2011 at 14:45  Add to Calendar ▼2011-06-30 14:45:002011-06-30 15:45:00Europe/LondonChaperone-Assisted Crystallography with DARPinsSELECTBIOenquiries@selectbiosciences.comA recurring effort to crystallize a particular protein is to bind it non-covalently to a specific helper binding protein – a crystallization chaperone. There is a wide range of tools available nowadays but their handling is often not as convenient as required. A valuable addition to the present repertoire of binding proteins is the designed ankyrin repeat protein (DARPin) technology. The potential of these novel binding proteins is illustrated by co-crystal structures with a variety of target proteins, including a membrane protein. The usefulness of DARPins in crystallization, the potential for phasing through DARPins and other recent approaches will be presented. |
Add to Calendar ▼2011-06-30 00:00:002011-07-01 00:00:00Europe/LondonAdvances in Protein CrystallographySELECTBIOenquiries@selectbiosciences.com
