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SELECTBIO Conferences Advances in qPCR

Mike Makrigiorgos's Biography



Mike Makrigiorgos, Professor, Dana-Farber Cancer Institute/Harvard Medical School

Dr. Makrigiorgos is Professor and Director of the Medical Physics and Biophysics Division of the combined Radiation Oncology Department at Dana Farber Cancer Institute, Brigham and Women’s and Children’s Hospitals, at Harvard Medical School, Boston, USA. He is also Director of the DNA technology laboratory and the radiation pre-clinical facility. He is a Member of the Editorial Board of Clinical Chemistry and has published over 100 articles, reviews and book chapters. His research interests include the development of novel DNA technologies for molecular diagnostics with application in Oncology. He is the inventor of several novel PCR-based techniques for molecular diagnostics, including Balanced-PCR, Anti-primer-quenching-real-time PCR, Hairpin-PCR and COLD-PCR.

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LNA-Enhanced Real-Time Ice-COLD-PCR and High Resolution Melting for Ultra-Sensitive Detection of Low-Level Lung Cancer Resistance Mutations

Tuesday, 26 April 2011 at 16:30

Add to Calendar ▼2011-04-26 16:30:002011-04-26 17:30:00Europe/LondonLNA-Enhanced Real-Time Ice-COLD-PCR and High Resolution Melting for Ultra-Sensitive Detection of Low-Level Lung Cancer Resistance MutationsAdvances in qPCR in BostonBostonSELECTBIOenquiries@selectbiosciences.com

We present ice-COLD-PCR, the 'next generation' of the previously described COLD-PCR technology, that can magnify and detect comprehensively traces of DNA alterations within a high excess of wild type samples. Using TP53 as an example we show an Increased and Complete Enrichment for all mutation types in lung cancer samples.


Add to Calendar ▼2011-04-26 00:00:002011-04-27 00:00:00Europe/LondonAdvances in qPCRAdvances in qPCR in BostonBostonSELECTBIOenquiries@selectbiosciences.com