Giovanni Vozzi,
Associate Professor, Dipartimento di Ingegneria dell’Informazione & Research Center ”E. Piaggio”,
University of Pisa
Giovanni Vozzi graduated in Electronic Engineering at University of Pisa and he got the PhD in Bioengineering at Politecnico of Milan. Actually he is Associate Professor in Bioengineering at University of Pisa. His research interests are: development of Biofabrication systems and of bioreactors; mechanical, chemical and cell characterization of new biomaterials; development of in silico cell models. He is Founding Member and member of Directors Board of International Society of Biofabrication. He has published more than 100 papers in international journals, 13 books chapters and he has developed 22 patents whose 6 are international.
How Is It Possible to Mimic the 3D Complexity of a Natural Tissue?
Friday, 8 June 2018 at 14:30
Add to Calendar ▼2018-06-08 14:30:002018-06-08 15:30:00Europe/LondonHow Is It Possible to Mimic the 3D Complexity of a Natural Tissue?Bioprinting and 3D-Printing in the Life Sciences EU 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
A biological tissue is a composite material with “bottom-up” hierarchical structure that is closely related to its heterogeneous function. The extracellular matrix modulates biochemical and biophysical signalling, and its rigidity is an important micro-environmental parameter that regulates the spatiotemporal dynamics of intercellular signalling. For this reason, many studies are focused on fabricating scaffolds processed at multiple scales with structural and mechanical properties that are optimal for eliciting specific response or mimic those found naturally. These scaffolds have to present large surface areas that have appropriate topology and biochemical cues (e.g. ligands) at the nanoscale for tissue adhesion, while also exhibiting integral porosity to allow for the exchange of molecules that maintain cellular function. In this talk, the use of multiscale and multimaterial processes will be presented to develop 3D in vitro models of bone that can mimic the 3D complexity of natural tissue, with applications in the study of physio-pathological conditions and for the analysis of effects of different biomolecules and/or drugs on cell activities. The combination of different natural and synthetic biomaterials, also in form of hydrogels and as suspension of bioactive glasses, processed with several bio-printheads in order to mimic the multiscale topology of natural tissue will be presented. The biomimicry of biochemical cues, given by appropriate growth factors, and the modulation of mechanical properties will demonstrated. Limitations and opportunities of these in vitro models will be discussed.
Add to Calendar ▼2018-06-07 00:00:002018-06-08 00:00:00Europe/LondonBioprinting and 3D-Printing in the Life Sciences EU 2018Bioprinting and 3D-Printing in the Life Sciences EU 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2018-06-08 14:30:002018-06-08 15:30:00Europe/LondonHow Is It Possible to Mimic the 3D Complexity of a Natural Tissue?Bioprinting and 3D-Printing in the Life Sciences EU 2018 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
