Gabriela Graziani,
Assistant Professor,
Politecnico di Milano
Dr. Gabriela Graziani is Assistant Professor in Bioengineering at Polytechnic University of Milan, where she conducts research regarding materials science applied to orthopaedics, with a special focus on materials for spine surgery, including new antibacterial, bioactive and anti-tumor materials and implants for the spine, new materials for disk regeneration, and tissue models, also obtained by combination of additive manufacturing and nanomaterials. She obtained her Master Degree (2012) and her PhD (2016) in Engineering at the University of Bologna, where she also served at as post-doc researcher. She has been researcher at Rizzoli Orthopaedic Institute from 2017 to 2023 and adjunct professor of Ceramic Materials at the University of Bologna from 2016 to 2019. She spent research periods abroad, including 6 months as a Visiting Student Research Collaborator at Princeton University (2014-2105), under the supervision of prof. George Scherer and 2 months as a Visiting Scholar at the New York University (2023).
Her research was awarded with several prices including the ON-EORS award in 2021, a 10.000 AlmaCurie prize from the University of Bologna for participation to the MSCA call 2021, a 10.000 prize for start-up ideas (Programme Reactor, Fondazione Golinelli, Bologna) and by a visiting and training period at the “Mind The Bridge Startup School” (San Francisco, CA). She is board member of the European Orthopaedic Research Society (EORS), where she serves as Secretary General and Co-chair of the awards committee, and a Member of the Industry Alliance Committee and Innovation Committee of the Orthopaedic Research Society (ORS). She also serves as Industry Liaison Officer in the Young Scientist Forum of the European Society for Biomaterials (ESB-YSF). Previously, she served in the Young Investigators committee of the EORS (2020-2022). She is a member of the Cost Action NetwOArk (CA21110 “Building an open European Network on OsteoArthritis research”, 2022-on) and of the EUSOA congress working group (09/2023-on). She served as scientific committee member and chair, invited speaker, session co-chair and has co-organized several workshops and symposia at international conferences. She received funding from Principal Investigator of the project “A new strategy to address tumor relapses by nanostructured implantable devices”, financed by the Italian Ministry of Health and devoted to antimicrobial and antitumor materials for spine metastases, WP leader of projects funded by the Royal Society of Edinburgh, Scottish Funding Council and the Scottish Government (RSE Saltire International Collaboration Award) and by the Italian Ministry of Economy and Finance (5 per mille for Scientific Research) and key person of the Euronanomed Project “NANOVERTEBRA - Next generation antibacterial nanostructured osseointegrated customized vertebral replacement”.
Additive Manufacturing and Nanomaterials-based Platforms For Bone Modeling and Regeneration: Controlling Cell Fate by Combined Compositional and Morphological Cues
Monday, 7 November 2022 at 15:00
Add to Calendar ▼2022-11-07 15:00:002022-11-07 16:00:00Europe/LondonAdditive Manufacturing and Nanomaterials-based Platforms For Bone Modeling and Regeneration: Controlling Cell Fate by Combined Compositional and Morphological CuesBioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com
Bone is a hierarchical tissue, having complex morphology and composition. Hence, new approaches are needed to mimic its characteristics, to obtain bone models as well as for its regeneration. To fulfill these aims, a scaffold or models shall reproduce as closely as possible the composition of native bone, because mimicking the native tissue permits boosting bone regeneration, and because bone apatite has a critical role in modulating the behavior of both healthy and tumor cells in the models. At the same time, morphological characteristics (i.e. porosity, surface morphology and roughness) are fundamental to determine the mechanical behavior of the model and to provide cues to which cells can react and that influence their morphology, adhesion, proliferation and differentiation. Here we propose new routes for obtaining bone-mimetic materials, by combining additive manufacturing techniques (3d printing and electrospinning) and plasma-assisted deposition of nano-structured coatings (Ionized Jet Deposition). By these techniques, we reproduce the characteristics of the native tissue and guide its regeneration, exploiting biomimicry, morphological and compositional cues and we study their interactions with healthy (MSCs) and tumor (SAOS-2) cells, for applications in bone regeneration and modeling.
Add to Calendar ▼2022-11-07 00:00:002022-11-08 00:00:00Europe/LondonBioprinting and Bioink Innovations for 3D-Tissues 2022Bioprinting and Bioink Innovations for 3D-Tissues 2022 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com