Highly Sensitive Cell Model for Botulinum Neurotoxin Detection Using Human Neurons from Induced Pluripotent Stem Cells.Wednesday, 23 January 2013 at 10:00 Add to Calendar ▼2013-01-23 10:00:002013-01-23 11:00:00Europe/LondonHighly Sensitive Cell Model for Botulinum Neurotoxin Detection Using Human Neurons from Induced Pluripotent Stem Cells. SELECTBIOenquiries@selectbiosciences.com Currently, several neuronal cell models exist for botulinum toxin detection, but none achieve high sensitivity with species-specific relevance. The most sensitive cell models are mouse or rat primary cells and neurons from mouse embryonic stem cells, but these require significant technical expertise for cell preparation. Neurons derived from hiPS cells provide a highly sensitive, reproducible, and human in vitro cell model for BoNT activity and neutralizing antibody detection, as well as for basic research. |