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SELECTBIO Conferences Discovery Chemistry Congress

Bogdan Iorga's Biography



Bogdan Iorga, Team Leader, Centre National De La Recherche Scientifique

Dr. Bogdan I. Iorga is the head of the Molecular Modelling and Structural Crystallography team at the Institut de Chimie des Substances Naturelles (CNRS, Gif-sur-Yvette, France), member of the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT). He received a M.Sc. (1997) and a Ph.D. (2001) in Chemistry from the Ecole Polytechnique (Palaiseau, France). In 2003, he joined the CNRS as a permanent researcher, working on total synthesis and molecular modeling in the area of neurotransmitter receptors. Dr. Iorga’s current scientific interests include drug design and development of new methodologies in molecular modeling. He co-authored a book (CRC Press, 2003), presenting the state of the art in phosphonate chemistry, and several book chapters.

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Conformational Flexibility in Drug Design of Anti-apoptotic Proteins Inhibitors

Wednesday, 19 February 2014 at 14:15

Add to Calendar ▼2014-02-19 14:15:002014-02-19 15:15:00Europe/LondonConformational Flexibility in Drug Design of Anti-apoptotic Proteins InhibitorsDiscovery Chemistry Congress in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com

Inhibitors derived from the natural compound meiogynine A, targeting the anti-apoptotic proteins Bcl-xL and Mcl-1, were designed using virtual screening of focused ligand libraries on selected representative protein conformations generated by all-atom molecular dynamics simulations.


Add to Calendar ▼2014-02-18 00:00:002014-02-19 00:00:00Europe/LondonDiscovery Chemistry CongressDiscovery Chemistry Congress in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com