Expanding the Scope of Fragment-Based Hit Identification: Targeting Novel Mechanisms in CancerTuesday, 18 February 2014 at 15:00 Add to Calendar ▼2014-02-18 15:00:002014-02-18 16:00:00Europe/LondonExpanding the Scope of Fragment-Based Hit Identification: Targeting Novel Mechanisms in CancerDiscovery Chemistry Congress in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com This presentation will outline our approach to targeting a novel protein-protein interaction implicated in invasion and metastasis. A biophysical screening platform was used to identify and validate hits followed by structure generation coupled with medicinal chemistry to optimise these compounds. |