Matthias Nees's Biography

Matthias Nees, Principal Scientist, VTT Technical Research Centre

Dr. Nees has generated advanced cell & tissue culture models since his PhD thesis at the German Cancer Research Centre (DKFZ), continued with organotypic cultures during postdoctoral work at NCI and U Heidelberg/EMBL, and now leads VTT’s Cancer Models group. In basic and contract research, also within the IMI PREDECT consortium, his goals are to generate complex, standardized and miniaturized organotypic models in vitro that mimic the heterogeneity and histology of human cancers. The main tasks include tumour/stroma interactions, remodelling of the tumour microenvironment, epithelial plasticity, cell invasion and motility. Simultaneously, these experimental platforms support high content screening and imaging methods.

Goodbye Petri Dish - Complex Cell and Tissue Culture Models for Drug Discovery and Toxicology

Thursday, 6 June 2013 at 10:45

Add to Calendar ▼2013-06-06 10:45:002013-06-06 11:45:00Europe/LondonGoodbye Petri Dish - Complex Cell and Tissue Culture Models for Drug Discovery and Toxicology SELECTBIOenquiries@selectbiosciences.com

The talk will introduce standardized and miniaturized, organotypic co-culture methods that allow mimicking the impact of cell-cell interactions, extracellular matrix and the (tumor) microenvironment on morphology and phenotype of complex epithelial tissues. Real time, live cell imaging and automated image analysis tools will be introduced. These enabling platforms allow high content screening and assays for drug discovery, target validation, and toxicology.

Add to Calendar ▼2013-06-06 00:00:002013-06-07 00:00:00Europe/LondonDrug Discovery Automation: High-content Screening and Cell Based AssaysSELECTBIOenquiries@selectbiosciences.com

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